Biophysical Approaches Determining Ligand Binding to Biomolecular Targets

Download or Read eBook Biophysical Approaches Determining Ligand Binding to Biomolecular Targets PDF written by Alberto Podjarny and published by Royal Society of Chemistry. This book was released on 2011-04-01 with total page 373 pages. Available in PDF, EPUB and Kindle.
Biophysical Approaches Determining Ligand Binding to Biomolecular Targets
Author :
Publisher : Royal Society of Chemistry
Total Pages : 373
Release :
ISBN-10 : 9781849732666
ISBN-13 : 1849732663
Rating : 4/5 (66 Downloads)

Book Synopsis Biophysical Approaches Determining Ligand Binding to Biomolecular Targets by : Alberto Podjarny

Book excerpt: The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available.


Biophysical Approaches Determining Ligand Binding to Biomolecular Targets Related Books

Biophysical Approaches Determining Ligand Binding to Biomolecular Targets
Language: en
Pages: 373
Authors: Alberto Podjarny
Categories: Science
Type: BOOK - Published: 2011 - Publisher: Royal Society of Chemistry

DOWNLOAD EBOOK

This book provides a complete overview of current techniques to identify ligands, characterize their binding sites, and understand binding mechanisms. Suitable
Biophysical Approaches Determining Ligand Binding to Biomolecular Targets
Language: en
Pages: 373
Authors: Alberto Podjarny
Categories: Science
Type: BOOK - Published: 2011-04-01 - Publisher: Royal Society of Chemistry

DOWNLOAD EBOOK

The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an inc
Protein-Ligand Interactions
Language: en
Pages: 0
Authors: Mark A. Williams
Categories: Science
Type: BOOK - Published: 2016-11-17 - Publisher: Humana

DOWNLOAD EBOOK

Proteins are the cell’s workers, their messengers and overseers. In these roles, proteins specifically bind small molecules, nucleic acid and other protein pa
Recent Developments in Biomolecular NMR
Language: en
Pages: 362
Authors: Marius Clore
Categories: Science
Type: BOOK - Published: 2012 - Publisher: Royal Society of Chemistry

DOWNLOAD EBOOK

This text draws together experts in the field to discuss advances in nuclear magnetic resonance methods that have occurred or had an impact on the biomolecular
Innovations in Biomolecular Modeling and Simulations
Language: en
Pages: 355
Authors: Tamar Schlick
Categories: Science
Type: BOOK - Published: 2012 - Publisher: Royal Society of Chemistry

DOWNLOAD EBOOK

This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts.