DNA and Chromatin Damage Caused by Radiation
| Author | : John T. Lett |
| Publisher | : Academic Press |
| Total Pages | : 520 |
| Release | : 2013-10-22 |
| ISBN-10 | : 9781483282275 |
| ISBN-13 | : 1483282279 |
| Rating | : 4/5 (75 Downloads) |
Book excerpt: Advances in Radiation Biology, Volume 17: DNA and Chromatin Damage Caused by Radiation outlines the different biological reactions to radiation. This book discusses the linear energy transfer and energy loss; DNA breaks and track structure; DNA radicals from water radicals; and radiation-induced strand breaks in isolated DNA. The radiation damage to DNA and its nearby environment; thiol radioprotectors and mechanism of action; radiolysis of water and track reactions; and computer simulation of higher order structure of DNA are also elaborated. This publication likewise covers the concept of chromatin structure; DNA supercoiling studied by sedimentation; measurement of radiation-induced DNA breakage; and analysis of damage in interphase cells. This volume is a useful reference to biologists and students concerned with DNA and chromatin damage caused by radiation.
