Free Energy Calculations in Rational Drug Design
Download or Read eBook Free Energy Calculations in Rational Drug Design PDF written by M. Rami Reddy and published by Springer Science & Business Media. This book was released on 2001-12-31 with total page 420 pages. Available in PDF, EPUB and Kindle.
| Author | : M. Rami Reddy |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 420 |
| Release | : 2001-12-31 |
| ISBN-10 | : 0306466767 |
| ISBN-13 | : 9780306466762 |
| Rating | : 4/5 (67 Downloads) |
Book Synopsis Free Energy Calculations in Rational Drug Design by : M. Rami Reddy
Book excerpt: Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities. Advances in computer power in the 1990s enabled the practical application of these calculations in rationale drug design. This book represents the first comprehensive review of this growing area of research and covers the basic theory underlying the method, numerous state of the art strategies designed to improve throughput and dozen examples wherein free energy calculations were used to design and evaluate potential drug candidates.
