Nanocarriers Based Colon Targeting

Book excerpt: Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies unveils a groundbreaking exploration of nanotechnology's potential in revolutionizing drug delivery for colon-related ailments. Nowadays, an array of colonic diseases, including colorectal cancer, colonic polyps, ulcerative colitis, and inflammatory bowel syndrome, pose significant medical challenges. This book delves into the intricate complexities of colonic diseases, their pathophysiology, and epidemiology to support pharmaceutical scientists in designing better drug delivery systems. Additionally, the book delves into cutting-edge topics such as gold nanoparticles, supramagnetic iron oxide nanoparticles, and protein-peptide-based nanoparticles, highlighting their mechanisms, applications, and potential toxicities.Providing a comprehensive overview of the area, the book's chapters elucidate diverse targeting strategies, from time-dependent to microbiota-based drug delivery systems, while also exploring receptor-based and magnetically-assisted delivery mechanisms. Case studies dissect the working mechanisms behind polymeric nanoparticles, polymersomes, polymeric micelles, solid lipid nanoparticles, and other nanocarrier systems tailored for colon targeting. - Introduces different colonic diseases and their pathophysiology - Explains the mechanism of action of different nanocarriers in colon targeting - Presents case studies of different nanocarriers in colon targeting - Explores peptide and proteins-based nanoparticles