The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of targe

The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of targe

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embar

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biolog

The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development