Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes

Download or Read eBook Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes PDF written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 18 pages. Available in PDF, EPUB and Kindle.
Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes
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Publisher : OECD Publishing
Total Pages : 18
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ISBN-10 : 9789264243088
ISBN-13 : 9264243089
Rating : 4/5 (88 Downloads)
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Book Synopsis Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes by : OECD

Book excerpt: The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In this test, the used genetic endpoints measure mutation at hypoxanthine-guanine phosphoribosyl transferase (HPRT), and at a transgene of xanthineguanine phosphoribosyl ...


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