The American Journal of Physiology, Vol. 7 (Classic Reprint)

Book excerpt: Excerpt from The American Journal of Physiology, Vol. 7 Although investigators do not agree as to the cause of coagulation, it is generally accorded that the coagulation temperatures of the different proteids may be modified considerably by the presence of a salt and by the reaction of the solution. The present work was undertaken at Dr. Loeb's suggestion and carried out under his direction to ascertain the effects of certain solutions upon (a) the temperature for the sudden coagulation of proteids in the muscle in situ, (b) the time necessary for coagulation at room temperature. On the Effects of Solutions upon the Coagulation Temperature of Muscle Substance. Method. - The gastrocnemius of the frog was used throughout the experiments. The muscle was placed in a covered dish containing 50 c.c. of the solution to be tested and was allowed to stand one hour at room temperature. It was then arranged for graphic registration upon the kymograph. A glass rod bent at right angles was screwed into the support holding the lever. The lower end of the rod drawn out to a fine point passed through the tendon of Achilles. The upper end of the muscle was attached to the short arm of the lever by means of a silk thread tied to a copper hook, which passed through the tendon covering the end of the femur. The solution was transferred to a beaker and arranged so that it surrounded the glass rod with it, attached muscle without touching the copper hook. A source of error pointed out by Vernon was thus avoided. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.