This book is being published at a time when opioid receptors have recently been cloned. The structural characteristics of opioid receptors and the recent advanc

This pocketbook summarizes the recent developments in this important and controversial aspect of pain management, looking at the benefits and adverse effects of

The interest in opioids such as morphine, the prototypical opioid ligand, has been maintained through the years. The identification of endogenous opioids and th

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the p

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how